Atopie

Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-α (peroxysome-proliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation…). A new emollient, containing a patented sunflower oleodistillate (SO), has been […]

Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-α (peroxysome-proliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation…). A new emollient, containing a patented sunflower oleodistillate (SO), has been [...]

Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. _ Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-a (peroxysomeproliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation. . .). A new emollient, containing a patented sunflower oleodistillate [...]

Objectives: During atopic dermatitis (AD), all washing products must preserve the mechanical and biologic skin barrier function, soothe the skin, and even improve other skin cares. For that purpose, a cosmetic baby product hygiene line dedicated to atopic skin has been developed. All three products are perfume and paraben free. They all contain mild vegetal […]

Objectives: Atopic dermatitis (AD) is a chronic dermatosis requiring permanent skin care. This goal can be achieved by emollients, often in conjunction with topical steroids if needed. In a previous study, an emollient containing a natural patented active ingredient (2% sunflower oleodistillate [SOD]) has demonstrated a 75% corticosteroid sparing effect (steroid class II, desonide 0.05%). […]

Emollients are commonly used for their effectiveness on atopic skin, supported by a few clinical studies suggesting their potential role as corticosteroid sparing agents. We investigated the effect of a new natural emollient on corticosteroid sparing and quality of life of young atopic children and their family. Eighty-six patients (4-48 mos) with moderate atopic dermatitis […]

Atopic dermatitis is a chronic relapsing inflammat-ry skin disease that affects 15–20% of children and 2–10% of adults worldwide. Topical treatments in-clude corticosteroids and calcineurin inhibitors, de-spite frequently observed adverse events, such as skin atrophy, itching and burning sensations. Alternative treatments that can prolong disease relief between flare-upsare therefore needed. A randomized, single-blind, placebo-controlled, multicentre [...]