Natural peroxisome proliferator-activated receptor-alpha agonist cream demonstrates similar therapeutic response to topical steroids in atopic dermatitis

25 November 2021

” Background: Atopic dermatitis (AD) requires permanent skin care. Objective: A cream containing 2% SO (sunflower oleodistillate), with peroxisome proliferator-activated receptor-alpha (PPAR-α) agonist properties, has been compared to a topical steroid (hydrocortisone butyro-propionate 1 mg/g). Methods: An open, randomized study included two groups of 40 children (aged 3 months to 4 years). Group A applied […]

Clinical Efficacy of Oligofructans from Ophiopogon japonicus in Reducing Atopic Dermatitis Flare-ups in Caucasian Patients

25 November 2021
Atopic dermatitis is a chronic relapsing inflammat-ry skin disease that affects 15–20% of children and 2–10% of adults worldwide. Topical treatments in-clude corticosteroids and calcineurin inhibitors, de-spite frequently observed adverse events, such as skin atrophy, itching and burning sensations. Alternative treatments that can prolong disease relief between flare-upsare therefore needed. A randomized, single-blind, placebo-controlled, multicentre [...]