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New therapeutic antiinflammatory action of a natural PPAR-alfa agonist emollient versus topical steroids in atopic dermatitis

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31 octobre 2022|
    Atopie

Objectives: Atopic dermatitis (AD) is a chronic dermatosis requiring permanent skin care. This goal can be achieved by emollients, often in conjunction with topical steroids if needed. In a previous study, an emollient containing a natural patented active ingredient (2% sunflower oleodistillate [SOD]) has demonstrated a 75% corticosteroid sparing effect (steroid class II, desonide 0.05%). […]

2009

Authors

Philippe Msika 1, Bernard Chadoutaud 2, Caroline Baudoin 1, Clarence de Belilovsky 3.

Affiliations

1 Laboratoires Expanscience, Epernon, France ; 2 Clinreal Online, Toulouse, France ; 3 Institut Alfred Fournier, Paris, France

Objectives: Atopic dermatitis (AD) is a chronic dermatosis requiring permanent skin care. This goal can be achieved by emollients, often in conjunction with topical steroids if needed. In a previous study, an emollient containing a natural patented active ingredient (2% sunflower oleodistillate [SOD]) has demonstrated a 75% corticosteroid sparing effect (steroid class II, desonide 0.05%). In this new European multicenter study, its applications have been compared to those of a more potent steroid (class III, hydrocortisone aceponate cream 1.27mg/g).