Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-α (peroxysome-proliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation…). A new emollient, containing a patented sunflower oleodistillate (SO), has been […]

Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-α (peroxysome-proliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation…). A new emollient, containing a patented sunflower oleodistillate (SO), has been [...]

Introduction: Atopic dermatitis (AD) is associated with skin barrier disruption resulting from major lipids metabolism dysfunctions. _ Dermo-corticosteroids (DC) are used for AD flares but have potential side effects. PPAR-a (peroxysomeproliferative-activated receptors) are transcription factors involved in the regulation of epidermal homeostasis (differentiation, proliferation, inflammation. . .). A new emollient, containing a patented sunflower oleodistillate [...]

Introduction: Irritant, allergic contact dermatitis (ICD, ACD), and atopic dermatitis (AD), beside therapeutic prescriptions, need a specific cosmetic management with emollient, antiirritant, antimicrobial, and healing products. A new emulsion for ICD and ACD with no antiseptic, no common preservative, no perfume, and no colorant has been developed. It contains the first oligo-element triad (Cu-Zn-Mn), phytosphingosines, [...]

Intracellular signal transduction pathways regulating melanogenesis imply PKC, camp through the activation of PKA and NO. A new whitening formulation, that targets these three different pathways, have been tested on melasma, with image analysis and a particular interest on the Qualiy of Life (QoL) of the volunteers. The tested product was a cosmetic cream containing [...]