” Background: Atopic dermatitis (AD) requires permanent skin care. Objective: A cream containing 2% SO (sunflower oleodistillate), with peroxisome proliferator-activated receptor-alpha (PPAR-α) agonist properties, has been compared to a topical steroid (hydrocortisone butyro-propionate 1 mg/g). Methods: An open, randomized study included two groups of 40 children (aged 3 months to 4 years). Group A applied […]

Atopic dermatitis is a chronic relapsing inflammat-ry skin disease that affects 15–20% of children and 2–10% of adults worldwide. Topical treatments in-clude corticosteroids and calcineurin inhibitors, de-spite frequently observed adverse events, such as skin atrophy, itching and burning sensations. Alternative treatments that can prolong disease relief between flare-upsare therefore needed. A randomized, single-blind, placebo-controlled, multicentre [...]

“Background: Pruritus is defined as an “unpleasant sensation that elicits the desire or reflex to scratch”. It can occur without injury or disease, serves no apparent biological purpose and has no recognizable endpoint. It appears along with a number of skin and systemic diseases. Aim: to determine the benefit of a novel topical anti-pruritic spray […]